RHAMM, a receptor for hyaluronan-mediated motility, compensates for CD44 in inflamed CD44-knockout mice: A different interpretation of redundancy

We report here that joint inflammation in collagen-induced arthritis is more aggravated in CD44-knockout mice than in WT mice, and we provide evidence for molecular redundancy as a causal factor. Furthermore, we show that under the inflammatory cascade, RHAMM (receptor for hyaluronan-mediated motili...

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Bibliografiske detaljer
Main Authors: Nedvetzki, Shlomo, Gonen, Erez, Assayag, Nathalie, Reich, Reuven, Williams, Richard O., Thurmond, Robin L., Huang, Jing-Feng, Neudecker, Birgit A., Wang, Fu-Shang, Turley, Eva A., Naor, David
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC539795/
https://ncbi.nlm.nih.gov/pubmed/15596723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407378102
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