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Emergent trade-offs and selection for outbreak frequency in spatial epidemics

Nonspatial theory on pathogen evolution generally predicts selection for maximal number of secondary infections, constrained only by supposed physiological trade-offs between pathogen infectiousness and virulence. Spread of diseases in human populations can, however, exhibit large scale patterns, un...

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Detalhes bibliográficos
Main Authors: van Ballegooijen, W. Marijn, Boerlijst, Maarten C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC539754/
https://ncbi.nlm.nih.gov/pubmed/15604150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405682101
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