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Per-Arnt-Sim domain-dependent association of cAMP-phosphodiesterase 8A1 with IκB proteins

Phosphodiesterase (PDE) 8A1 is a cAMP-specific PDE isozyme characterized by the presence of a Per-Arnt-Sim (PAS) domain. However, the function(s) of the PAS domain has remained unknown. In this study, using a lysate of HEK293 cells overexpressing recombinant human PDE8A1, we detected a physical asso...

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Detalhes bibliográficos
Main Authors: Wu, Ping, Wang, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC539753/
https://ncbi.nlm.nih.gov/pubmed/15596729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407649101
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