Menadione metabolism to thiodione in hepatoblastoma by scanning electrochemical microscopy
The cytotoxicity of menadione on hepatocytes was studied by using the substrate generation/tip collection mode of scanning electrochemical microscopy by exposing the cells to menadione and detecting the menadione-S-glutathione conjugate (thiodione) that is formed during the cellular detoxication pro...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC539751/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15601769/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0407613101 |
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