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Menadione metabolism to thiodione in hepatoblastoma by scanning electrochemical microscopy

The cytotoxicity of menadione on hepatocytes was studied by using the substrate generation/tip collection mode of scanning electrochemical microscopy by exposing the cells to menadione and detecting the menadione-S-glutathione conjugate (thiodione) that is formed during the cellular detoxication pro...

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Detalhes bibliográficos
Main Authors: Mauzeroll, Janine, Bard, Allen J., Owhadian, Omeed, Monks, Terrence J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC539751/
https://ncbi.nlm.nih.gov/pubmed/15601769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407613101
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