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Insufficient levels of the nrdAB-encoded ribonucleotide reductase underlie the severe growth defect of the Δhda E. coli strain

The ATP-bound form of the Escherichia coli DnaA replication initiator protein remodels the chromosomal origin of replication, oriC, to load the replicative helicase. The primary mechanism for regulating the activity of DnaA involves the Hda and β clamp proteins, which act together to dramatically st...

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Détails bibliographiques
Publié dans:Mol Microbiol
Auteurs principaux: Babu, Vignesh M. P., Itsko, Mark, Baxter, Jamie C., Schaaper, Roel M., Sutton, Mark D.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397354/
https://ncbi.nlm.nih.gov/pubmed/28130843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13632
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