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Insufficient levels of the nrdAB-encoded ribonucleotide reductase underlie the severe growth defect of the Δhda E. coli strain

The ATP-bound form of the Escherichia coli DnaA replication initiator protein remodels the chromosomal origin of replication, oriC, to load the replicative helicase. The primary mechanism for regulating the activity of DnaA involves the Hda and β clamp proteins, which act together to dramatically st...

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Bibliografiset tiedot
Julkaisussa:Mol Microbiol
Päätekijät: Babu, Vignesh M. P., Itsko, Mark, Baxter, Jamie C., Schaaper, Roel M., Sutton, Mark D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397354/
https://ncbi.nlm.nih.gov/pubmed/28130843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13632
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