Expression of the eRF1 translation termination factor is controlled by an autoregulatory circuit involving readthrough and nonsense-mediated decay in plants

When a ribosome reaches a stop codon, the eukaryotic Release Factor 1 (eRF1) binds to the A site of the ribosome and terminates translation. In yeasts and plants, both over- and underexpression of eRF1 lead to altered phenotype indicating that eRF1 expression should be strictly controlled. However,...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Nyikó, Tünde, Auber, Andor, Szabadkai, Levente, Benkovics, Anna, Auth, Mariann, Mérai, Zsuzsanna, Kerényi, Zoltán, Dinnyés, Andrea, Nagy, Ferenc, Silhavy, Dániel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
Soggetti:
RNA
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397192/
https://ncbi.nlm.nih.gov/pubmed/28062855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1303
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