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A murine preclinical syngeneic transplantation model for breast cancer precision medicine

We previously demonstrated that altered activity of lysophosphatidic acid in murine mammary glands promotes tumorigenesis. We have now established and characterized a heterogeneous collection of mouse-derived syngeneic transplants (MDSTs) as preclinical platforms for the assessment of personalized p...

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Bibliographic Details
Published in:Sci Adv
Main Authors: Federico, Lorenzo, Chong, Zechen, Zhang, Dong, McGrail, Daniel J., Zhao, Wei, Jeong, Kang Jin, Vellano, Christopher P., Ju, Zhenlin, Gagea, Mihai, Liu, Shuying, Mitra, Shreya, Dennison, Jennifer B., Lorenzi, Philip L., Cardnell, Robert, Diao, Lixia, Wang, Jing, Lu, Yiling, Byers, Lauren A., Perou, Charles M., Lin, Shiaw-Yih, Mills, Gordon B.
Format: Artigo
Language:Inglês
Published: American Association for the Advancement of Science 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397135/
https://ncbi.nlm.nih.gov/pubmed/28439535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1600957
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