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Promoter hypermethylation as a mechanism for Lamin A/C silencing in a subset of neuroblastoma cells

Nuclear lamins support the nuclear envelope and provide anchorage sites for chromatin. They are involved in DNA synthesis, transcription, and replication. It has previously been reported that the lack of Lamin A/C expression in lymphoma and leukaemia is due to CpG island promoter hypermethylation. H...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Rauschert, Ines, Aldunate, Fabian, Preussner, Jens, Arocena-Sutz, Miguel, Peraza, Vanina, Looso, Mario, Benech, Juan C., Agrelo, Ruben
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397038/
https://ncbi.nlm.nih.gov/pubmed/28422997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175953
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