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Inflammation-induced fetal growth restriction in rats is associated with increased placental HIF-1α accumulation

INTRODUCTION: Hypoxia-inducible factor 1-alpha (HIF-1α) is the oxygen-sensitive subunit of the transcription factor HIF-1, and its expression is increased in placentas from pregnancies complicated by pre-eclampsia (PE). Fetal growth restriction (FGR) and PE often share a common pathophysiology; howe...

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Pubblicato in:PLoS One
Autori principali: Robb, Kevin P., Cotechini, Tiziana, Allaire, Camille, Sperou, Arissa, Graham, Charles H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397034/
https://ncbi.nlm.nih.gov/pubmed/28423052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175805
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