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Inflammation in rat pregnancy inhibits spiral artery remodeling leading to fetal growth restriction and features of preeclampsia

Fetal growth restriction (FGR) and preeclampsia (PE) are often associated with abnormal maternal inflammation, deficient spiral artery (SA) remodeling, and altered uteroplacental perfusion. Here, we provide evidence of a novel mechanistic link between abnormal maternal inflammation and the developme...

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Autors principals: Cotechini, Tiziana, Komisarenko, Maria, Sperou, Arissa, Macdonald-Goodfellow, Shannyn, Adams, Michael A., Graham, Charles H.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892976/
https://ncbi.nlm.nih.gov/pubmed/24395887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130295
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