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Inflammation in rat pregnancy inhibits spiral artery remodeling leading to fetal growth restriction and features of preeclampsia

Fetal growth restriction (FGR) and preeclampsia (PE) are often associated with abnormal maternal inflammation, deficient spiral artery (SA) remodeling, and altered uteroplacental perfusion. Here, we provide evidence of a novel mechanistic link between abnormal maternal inflammation and the developme...

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Bibliografiske detaljer
Main Authors: Cotechini, Tiziana, Komisarenko, Maria, Sperou, Arissa, Macdonald-Goodfellow, Shannyn, Adams, Michael A., Graham, Charles H.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892976/
https://ncbi.nlm.nih.gov/pubmed/24395887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130295
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