Targeted delivery of thymosin beta 4 to the injured myocardium using CREKA-conjugated nanoparticles

PURPOSE: Thymosin beta 4 (Tβ4) has multiple beneficial facets for myocardial injury, but its efficiency is limited by the low local concentration within the infarct. Here, we established a Tβ4 delivery system for cardiac repair based on the interaction between the abundant fibrin in the infarct zone...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Huang, Zheyong, Song, Yanan, Pang, Zhiqing, Zhang, Bo, Yang, Hongbo, Shi, Hongtao, Chen, Jing, Gong, Hui, Qian, Juying, Ge, Junbo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396927/
https://ncbi.nlm.nih.gov/pubmed/28442910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S131949
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