Obesity-induced hepatic steatosis is mediated by endoplasmic reticulum stress in the subfornical organ of the brain

Nonalcoholic fatty liver disease (NAFLD), characterized by an excess accumulation of hepatic triglycerides, is a growing health epidemic. While ER stress in the liver has been implicated in the development of NAFLD, the role of brain ER stress — which is emerging as a key contributor to a number of...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Horwath, Julie A., Hurr, Chansol, Butler, Scott D., Guruju, Mallikarjun, Cassell, Martin D., Mark, Allyn L., Davisson, Robin L., Young, Colin N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396512/
https://ncbi.nlm.nih.gov/pubmed/28422749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90170
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