Deletion of p22(phox)-dependent oxidative stress in the hypothalamus protects against obesity by modulating β(3)-adrenergic mechanisms

A role for oxidative stress in the brain has been suggested in the pathogenesis of diet-induced obesity (DIO), although the underlying neural regions and mechanisms remain incompletely defined. We tested the hypothesis that NADPH oxidase–dependent oxidative stress in the paraventricular nucleus (PVN...

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Bibliografiset tiedot
Julkaisussa:JCI Insight
Päätekijät: Lob, Heinrich E., Song, Jiunn, Hurr, Chansol, Chung, Alvin, Young, Colin N., Mark, Allyn L., Davisson, Robin L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2017
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5256131/
https://ncbi.nlm.nih.gov/pubmed/28138551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87094
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