The group II metabotropic glutamate receptor agonist LY354740 and the D2 receptor antagonist haloperidol reduce locomotor hyperactivity but fail to rescue spatial working memory in GluA1 knockout mice

Group II metabotropic glutamate receptor agonists have been suggested as potential anti‐psychotics, at least in part, based on the observation that the agonist LY354740 appeared to rescue the cognitive deficits caused by non‐competitive N‐methyl‐d‐aspartate receptor (NMDAR) antagonists, including sp...

Full description

Saved in:
Bibliographic Details
Published in:Eur J Neurosci
Main Authors: Boerner, Thomas, Bygrave, Alexei M., Chen, Jingkai, Fernando, Anushka, Jackson, Stephanie, Barkus, Chris, Sprengel, Rolf, Seeburg, Peter H., Harrison, Paul J., Gilmour, Gary, Bannerman, David M., Sanderson, David J.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
Subjects:
Behavioural Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396315/
https://ncbi.nlm.nih.gov/pubmed/28186680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.13539
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items