The group II metabotropic glutamate receptor agonist LY354740 and the D2 receptor antagonist haloperidol reduce locomotor hyperactivity but fail to rescue spatial working memory in GluA1 knockout mice

Group II metabotropic glutamate receptor agonists have been suggested as potential anti‐psychotics, at least in part, based on the observation that the agonist LY354740 appeared to rescue the cognitive deficits caused by non‐competitive N‐methyl‐d‐aspartate receptor (NMDAR) antagonists, including sp...

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Detaylı Bibliyografya
Yayımlandı:Eur J Neurosci
Asıl Yazarlar: Boerner, Thomas, Bygrave, Alexei M., Chen, Jingkai, Fernando, Anushka, Jackson, Stephanie, Barkus, Chris, Sprengel, Rolf, Seeburg, Peter H., Harrison, Paul J., Gilmour, Gary, Bannerman, David M., Sanderson, David J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2017
Konular:
Behavioural Neuroscience
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396315/
https://ncbi.nlm.nih.gov/pubmed/28186680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.13539
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