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Ammonia mediates cortical hemichannel dysfunction in rodent models of chronic liver disease
The pathogenesis of hepatic encephalopathy (HE) in cirrhosis is multifactorial and ammonia is thought to play a key role. Astroglial dysfunction is known to be present in HE. Astrocytes are extensively connected by gap junctions formed of connexins, which also exist as functional hemichannels allowi...
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| Pubblicato in: | Hepatology |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5396295/ https://ncbi.nlm.nih.gov/pubmed/28066916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29031 |
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