BCL2-mediated tumorigenicity of a human T-lymphoid cell line: synergy with MYC and inhibition by BCL2 antisense.

A gene-transfer approach was used to explore the function of the BCL2 (B-cell lymphoma/leukemia 2) gene in a human T-cell line, Jurkat. Though stable introduction of a BCL2 expression plasmid into Jurkat T cells was by itself insufficient, the combined transfer of BCL2 and MYC genes markedly enhance...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Reed, J C, Cuddy, M, Haldar, S, Croce, C, Nowell, P, Makover, D, Bradley, K
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1990
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC53962/
https://ncbi.nlm.nih.gov/pubmed/1692620
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