Assessment of copy number variation in genes related to drug resistance in Plasmodium vivax and Plasmodium falciparum isolates from the Brazilian Amazon and a systematic review of the literature

BACKGROUND: Parasite resistance to anti-malarials represents a great obstacle for malaria elimination. The majority of studies have investigated the association between single-nucleotide polymorphisms (SNPs) and drug resistance; however, it is becoming clear that the copy number variation (CNV) is a...

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Publicado en:Malar J
Autores principales: Costa, Gabriel Luíz, Amaral, Lara Cotta, Fontes, Cor Jesus Fernandes, Carvalho, Luzia Helena, de Brito, Cristiana Ferreira Alves, de Sousa, Taís Nóbrega
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395969/
https://ncbi.nlm.nih.gov/pubmed/28420389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-017-1806-z
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