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G protein-coupled KISS1 receptor is overexpressed in triple negative breast cancer and promotes drug resistance

Triple-negative breast cancer (TNBC) lacks the expression of estrogen receptor α, progesterone receptor and human epidermal growth factor receptor 2 (HER2). TNBC patients lack targeted therapies, as they fail to respond to endocrine and anti-HER2 therapy. Prognosis for this aggressive cancer subtype...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Blake, Alexandra, Dragan, Magdalena, Tirona, Rommel G., Hardy, Daniel B., Brackstone, Muriel, Tuck, Alan B., Babwah, Andy V., Bhattacharya, Moshmi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395950/
https://ncbi.nlm.nih.gov/pubmed/28422142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46525
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