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Chronic stress induces CD99, suppresses autophagy, and affects spontaneous adipogenesis in human bone marrow stromal cells

BACKGROUND: Bone marrow-derived mesenchymal stromal cells (MSCs) are multipotent cells with a high constitutive level of autophagy and low expression of CD99. Under certain conditions, MSCs may develop tumorigenic properties. However, these transformation-induced conditions are largely unknown. Rece...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Husak, Zvenyslava, Dworzak, Michael N.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395812/
https://ncbi.nlm.nih.gov/pubmed/28420430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0532-3
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