Rac1 GTPase silencing counteracts microgravity-induced effects on osteoblastic cells

Bone cells exposed to real microgravity display alterations of their cytoskeleton and focal adhesions, two major mechanosensitive structures. These structures are controlled by small GTPases of the Ras homology (Rho) family. We investigated the effects of RhoA, Rac1, and Cdc42 modulation of osteobla...

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Bibliografische gegevens
Gepubliceerd in:FASEB J
Hoofdauteurs: Guignandon, Alain, Faure, Céline, Neutelings, Thibaut, Rattner, Aline, Mineur, Pierre, Linossier, Marie-Thérèse, Laroche, Norbert, Lambert, Charles, Deroanne, Christophe, Nusgens, Betty, Demets, René, Colige, Alain, Vico, Laurence
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Federation of American Societies for Experimental Biology 2014
Onderwerpen:
Research Communications
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395736/
https://ncbi.nlm.nih.gov/pubmed/24903274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-249714
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