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The DnaK Chaperone Uses Different Mechanisms To Promote and Inhibit Replication of Vibrio cholerae Chromosome 2

Replication of Vibrio cholerae chromosome 2 (Chr2) depends on molecular chaperone DnaK to facilitate binding of the initiator (RctB) to the replication origin. The binding occurs at two kinds of site, 12-mers and 39-mers, which promote and inhibit replication, respectively. Here we show that DnaK em...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Jha, Jyoti K., Li, Mi, Ghirlando, Rodolfo, Miller Jenkins, Lisa M., Wlodawer, Alexander, Chattoraj, Dhruba
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395669/
https://ncbi.nlm.nih.gov/pubmed/28420739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00427-17
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