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Initiator protein dimerization plays a key role in replication control of Vibrio cholerae chromosome 2

RctB, the initiator of replication of Vibrio cholerae chromosome 2 (chr2), binds to the origin of replication to specific 12-mer sites both as a monomer and a dimer. Binding to 12-mers is essential for initiation. The monomers also bind to a second kind of site, 39-mers, which inhibits initiation. M...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jha, Jyoti K., Ghirlando, Rodolfo, Chattoraj, Dhruba K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176361/
https://ncbi.nlm.nih.gov/pubmed/25159619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku771
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