IQGAP1 Mediates Hcp1-Promoted Escherichia coli Meningitis by Stimulating the MAPK Pathway

Escherichia coli-induced meningitis remains a life-threatening disease despite recent advances in the field of antibiotics-based therapeutics, necessitating continued research on its pathogenesis. The current study aims to elucidate the mechanism through which hemolysin-coregulated protein 1 (Hcp1)...

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Bibliografiske detaljer
Udgivet i:Front Cell Infect Microbiol
Main Authors: Zhao, Mingna, Zhang, Lingfei, Lv, Shaogang, Zhang, Chenzi, Wang, Lin, Chen, Hong, Zhou, Yan, Lou, Jiatao
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395654/
https://ncbi.nlm.nih.gov/pubmed/28469997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00132
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