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A novel applicability domain technique for mapping predictive reliability across the chemical space of a QSAR: reliability-density neighbourhood

The ability to define the regions of chemical space where a predictive model can be safely used is a necessary condition to assure the reliability of new predictions. This implies that reliability must be determined across chemical space in the attempt to localize “safe” and “unsafe” regions for pre...

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Pubblicato in:J Cheminform
Autori principali: Aniceto, Natália, Freitas, Alex A., Bender, Andreas, Ghafourian, Taravat
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395519/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13321-016-0182-y
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