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Identification and characterization of a HeLa nuclear protein that specifically binds to the trans-activation-response (TAR) element of human immunodeficiency virus.

Human immunodeficiency virus type 1 RNAs contain a sequence, trans-activation-response (TAR) element, which is required for tat protein-mediated trans-activation of viral gene expression. We have identified a nuclear protein from extracts of HeLa cells that binds to the TAR element RNA in a sequence...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Marciniak, R A, Garcia-Blanco, M A, Sharp, P A
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1990
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53954/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2333305/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.9.3624
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