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Unbiased estimation for response adaptive clinical trials

Bayesian adaptive trials have the defining feature that the probability of randomization to a particular treatment arm can change as information becomes available as to its true worth. However, there is still a general reluctance to implement such designs in many clinical settings. One area of conce...

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Detalhes bibliográficos
Publicado no:Stat Methods Med Res
Main Authors: Bowden, Jack, Trippa, Lorenzo
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395089/
https://ncbi.nlm.nih.gov/pubmed/26265771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280215597716
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