Effects of egg-adaptation on receptor-binding and antigenic properties of recent influenza A (H3N2) vaccine viruses

Influenza A virus (subtype H3N2) causes seasonal human influenza and is included as a component of influenza vaccines. The majority of vaccine viruses are isolated and propagated in eggs, which commonly results in amino acid substitutions in the haemagglutinin (HA) glycoprotein. These substitutions...

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Detalhes bibliográficos
Publicado no:J Gen Virol
Main Authors: Parker, Lauren, Wharton, Stephen A., Martin, Stephen R., Cross, Karen, Lin, Yipu, Liu, Yan, Feizi, Ten, Daniels, Rodney S., McCauley, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2016
Assuntos:
Animal
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394856/
https://ncbi.nlm.nih.gov/pubmed/26974849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000457
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