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Focused antibody response to influenza linked to antigenic drift

The selective pressure that drives antigenic changes in influenza viruses is thought to originate from the human immune response. Here, we have characterized the B cell repertoire from a previously vaccinated donor whose serum had reduced neutralizing activity against the recently evolved clade 6B H...

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Huang, Kuan-Ying A., Rijal, Pramila, Schimanski, Lisa, Powell, Timothy J., Lin, Tzou-Yien, McCauley, John W., Daniels, Rodney S., Townsend, Alain R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613558/
https://ncbi.nlm.nih.gov/pubmed/26011643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81104
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