Focused antibody response to influenza linked to antigenic drift

The selective pressure that drives antigenic changes in influenza viruses is thought to originate from the human immune response. Here, we have characterized the B cell repertoire from a previously vaccinated donor whose serum had reduced neutralizing activity against the recently evolved clade 6B H...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Huang, Kuan-Ying A., Rijal, Pramila, Schimanski, Lisa, Powell, Timothy J., Lin, Tzou-Yien, McCauley, John W., Daniels, Rodney S., Townsend, Alain R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613558/
https://ncbi.nlm.nih.gov/pubmed/26011643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81104
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