Group V Secreted Phospholipase A(2) Induces the Release of Proangiogenic and Antiangiogenic Factors by Human Neutrophils

Secreted phospholipases A(2) (sPLA(2)s) are extracellular enzymes that catalyze the release of free fatty acids and lysophospholipids from membrane phospholipids and also bind to different receptors (e.g., PLA(2)R1 or integrins). To date, 12 mammalian sPLA(2)s have been identified, which play a crit...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Loffredo, Stefania, Borriello, Francesco, Iannone, Raffaella, Ferrara, Anne L., Galdiero, Maria R., Gigantino, Vincenzo, Esposito, Pasquale, Varricchi, Gilda, Lambeau, Gerard, Cassatella, Marco A., Granata, Francescopaolo, Marone, Gianni
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394767/
https://ncbi.nlm.nih.gov/pubmed/28458672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00443
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