The Cac2 subunit is essential for productive histone binding and nucleosome assembly in CAF-1

Nucleosome assembly following DNA replication controls epigenome maintenance and genome integrity. Chromatin assembly factor 1 (CAF-1) is the histone chaperone responsible for histone (H3-H4)(2) deposition following DNA synthesis. Structural and functional details for this chaperone complex and its...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Mattiroli, Francesca, Gu, Yajie, Balsbaugh, Jeremy L., Ahn, Natalie G., Luger, Karolin
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394680/
https://ncbi.nlm.nih.gov/pubmed/28418026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46274
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