The Cac1 subunit of histone chaperone CAF-1 organizes CAF-1-H3/H4 architecture and tetramerizes histones

The histone chaperone Chromatin Assembly Factor 1 (CAF-1) deposits tetrameric (H3/H4)(2) histones onto newly-synthesized DNA during DNA replication. To understand the mechanism of the tri-subunit CAF-1 complex in this process, we investigated the protein-protein interactions within the CAF-1-H3/H4 a...

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Udgivet i:eLife
Main Authors: Liu, Wallace H, Roemer, Sarah C, Zhou, Yeyun, Shen, Zih-Jie, Dennehey, Briana K, Balsbaugh, Jeremy L, Liddle, Jennifer C, Nemkov, Travis, Ahn, Natalie G, Hansen, Kirk C, Tyler, Jessica K, Churchill, Mair EA
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2016
Fag:
Biophysics and Structural Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045291/
https://ncbi.nlm.nih.gov/pubmed/27690308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.18023
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