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The Janus Kinase (JAK) FERM and SH2 Domains: Bringing Specificity to JAK–Receptor Interactions

The Janus kinases (JAKs) are non-receptor tyrosine kinases essential for signaling in response to cytokines and interferons and thereby control many essential functions in growth, development, and immune regulation. JAKs are unique among tyrosine kinases for their constitutive yet non-covalent assoc...

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書目詳細資料
發表在:Front Endocrinol (Lausanne)
Main Authors: Ferrao, Ryan, Lupardus, Patrick J.
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394478/
https://ncbi.nlm.nih.gov/pubmed/28458652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2017.00071
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