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Cis-Regulatory Circuits Regulating NEK6 Kinase Overexpression in Transformed B Cells Are Super-Enhancer-Independent

Alterations in distal regulatory elements that control gene expression underlie many diseases, including cancer. Epigenomic analyses of normal and diseased cells have produced correlative predictions for connections between dysregulated enhancers and target genes involved in pathogenesis. However, w...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Huang, Yue, Koues, Olivia I., Zhao, Jiang-yang, Liu, Regina, Pyfrom, Sarah C., Payton, Jacqueline E., Oltz, Eugene M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393904/
https://ncbi.nlm.nih.gov/pubmed/28329684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.02.067
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