A Phase 2 Study of Chronocort, a Modified-Release Formulation of Hydrocortisone, in the Treatment of Adults With Classic Congenital Adrenal Hyperplasia

CONTEXT: Treatment of congenital adrenal hyperplasia (CAH) is suboptimal. Inadequate suppression of androgens and glucocorticoid excess are common and current glucocorticoid formulations cannot replace the cortisol circadian rhythm. OBJECTIVES: The primary objective was to characterize the pharmacok...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Mallappa, Ashwini, Sinaii, Ninet, Kumar, Parag, Whitaker, Martin J., Daley, Lori-Ann, Digweed, Dena, Eckland, David J. A., Van Ryzin, Carol, Nieman, Lynnette K., Arlt, Wiebke, Ross, Richard J., Merke, Deborah P.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393506/
https://ncbi.nlm.nih.gov/pubmed/25494662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-3809
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