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The Sonic Hedgehog Signaling Pathway Maintains the Cancer Stem Cell Self-Renewal of Anaplastic Thyroid Cancer by Inducing Snail Expression

CONTEXT: Cancer stem cells (CSCs) have been recently identified in thyroid neoplasm. Anaplastic thyroid cancer (ATC) contains a higher percentage of CSCs than well-differentiated thyroid cancer. The signaling pathways and the transcription factors that regulate thyroid CSC self-renewal remain poorly...

詳細記述

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書誌詳細
出版年:J Clin Endocrinol Metab
主要な著者: Heiden, Katherine B., Williamson, Ashley J., Doscas, Michelle E., Ye, Jin, Wang, Yimin, Liu, Dingxie, Xing, Mingzhao, Prinz, Richard A., Xu, Xiulong
フォーマット: Artigo
言語:Inglês
出版事項: Endocrine Society 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393503/
https://ncbi.nlm.nih.gov/pubmed/25078145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-1844
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