The Effect of Leptin Replacement on Parathyroid Hormone, RANKL-Osteoprotegerin Axis, and Wnt Inhibitors in Young Women With Hypothalamic Amenorrhea

CONTEXT: Recombinant leptin (metreleptin) treatment restores bone mineral density in women with hypothalamic amenorrhea (HA), a condition characterized by hypoleptinemia, which has adverse impact on bone health. OBJECTIVE: The objective of the study was to investigate how metreleptin exerts its posi...

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Bibliografiske detaljer
Udgivet i:J Clin Endocrinol Metab
Main Authors: Foo, Joo-Pin, Polyzos, Stergios A., Anastasilakis, Athanasios D., Chou, Sharon, Mantzoros, Christos S.
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2014
Fag:
Hot Topics in Translational Endocrinology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393498/
https://ncbi.nlm.nih.gov/pubmed/25148234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-2491
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