Preadipocyte Factor-1 Levels Are Higher in Women with Hypothalamic Amenorrhea and Are Associated with Bone Mineral Content and Bone Mineral Density through a Mechanism Independent of Leptin

CONTEXT: Preadipocyte factor 1 (pref-1) is increased in anorexia nervosa and is associated negatively with bone mineral density (BMD). No previous studies exist on pref-1 in women with exercise-induced hypothalamic amenorrhea (HA), which similar to anorexia nervosa, is an energy-deficiency state ass...

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Bibliographic Details
Main Authors: Aronis, Konstantinos N., Kilim, Holly, Chamberland, John P., Breggia, Anne, Rosen, Clifford, Mantzoros, Christos S.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2011
Subjects:
JCEM Online: Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3200235/
https://ncbi.nlm.nih.gov/pubmed/21795455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2011-0600
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