Development of an Enhanced Sensitivity Bead-Based Immunoassay for Real-Time In Vivo Detection of Pancreatic β-Cell Death

There is a clinical need for plasma tests to detect and quantify the in vivo destruction of pancreatic β-cells in type 1 diabetes. We previously developed a time-resolved fluorescence immunoassay (TRFIA) to glutamate decarboxylase 65 kDa (GAD65) (GAD65-TRFIA) that was able to detect the synchronous...

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Dettagli Bibliografici
Pubblicato in:Endocrinology
Autori principali: Costa, Olivier R., Stangé, Geert, Verhaeghen, Katrijn, Brackeva, Benedicte, Nonneman, Ellen, Hampe, Christiane S., Ling, Zhidong, Pipeleers, Daniel, Gorus, Frans K., Martens, Geert A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2015
Soggetti:
Technical Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393343/
https://ncbi.nlm.nih.gov/pubmed/26431226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1636
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