Potential of Protein Phosphatase Inhibitor 1 As Biomarker of Pancreatic β-Cell Injury In Vitro and In Vivo

There is a need for plasma-based tests that can directly measure the extent of β-cell injury in vivo in patients receiving islet grafts and in animal models. In this study, we propose protein phosphatase 1, regulatory (inhibitor) subunit 1A (PPP1R1A) as a novel biomarker for acute β-cell destruction...

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Main Authors: Jiang, Lei, Brackeva, Benedicte, Ling, Zhidong, Kramer, Gertjan, Aerts, Johannes M., Schuit, Frans, Keymeulen, Bart, Pipeleers, Daniel, Gorus, Frans, Martens, Geert A.
Formato: Artigo
Idioma:Inglês
Publicado: American Diabetes Association 2013
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717856/
https://ncbi.nlm.nih.gov/pubmed/23557701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1507
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