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A Model of the Statistical Power of Comparative Genome Sequence Analysis

Comparative genome sequence analysis is powerful, but sequencing genomes is expensive. It is desirable to be able to predict how many genomes are needed for comparative genomics, and at what evolutionary distances. Here I describe a simple mathematical model for the common problem of identifying con...

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Detalhes bibliográficos
Autor principal: Eddy, Sean R
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC539325/
https://ncbi.nlm.nih.gov/pubmed/15660152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0030010
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