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Nurr1:RXRα heterodimer activation as monotherapy for Parkinson’s disease

Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic (DAergic) neurons in the substantia nigra and the gradual depletion of dopamine (DA). Current treatments replenish the DA deficit and improve symptoms but induce dyskinesias over time, and...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Spathis, Athanasios D., Asvos, Xenophon, Ziavra, Despina, Karampelas, Theodoros, Topouzis, Stavros, Cournia, Zoe, Qing, Xiaobing, Alexakos, Pavlos, Smits, Lisa M., Dalla, Christina, Rideout, Hardy J., Schwamborn, Jens Christian, Tamvakopoulos, Constantin, Fokas, Demosthenes, Vassilatis, Demetrios K.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393203/
https://ncbi.nlm.nih.gov/pubmed/28348207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616874114
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