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How to Measure Drug Transport across the Blood-Brain Barrier

Summary: The extent to which a substance in the circulation gains access to the CNS needs to be determined for potential neuropharmaceuticals as well as for drug candidates with primary targets in the periphery. Characteristics of the in vivo methods, ranging from classical pharmacokinetic technique...

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Autor principal: Bickel, Ulrich
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Experimental NeuroTherapeutics, Inc. 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC539317/
https://ncbi.nlm.nih.gov/pubmed/15717054
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