A carregar...
Amino acid substitution equivalent to human chorea-acanthocytosis I2771R in yeast Vps13 protein affects its binding to phosphatidylinositol 3-phosphate
The rare human disorder chorea-acanthocytosis (ChAc) is caused by mutations in hVPS13A gene. The hVps13A protein interacts with actin and regulates the level of phosphatidylinositol 4-phosphate (PI4P) in the membranes of neuronal cells. Yeast Vps13 is involved in vacuolar protein transport and, like...
Na minha lista:
| Publicado no: | Hum Mol Genet |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5393151/ https://ncbi.nlm.nih.gov/pubmed/28334785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx054 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|