Opioid Receptor Activity and Analgesic Potency of DPDPE Peptide Analogues Containing a Xylene Bridge

[Image: see text] d-Pen(2),d-Pen(5) enkephalin (DPDPE) is one of the most selective synthetic peptide agonists targeting the δ-opioid receptor. Three cyclic analogues of DPDPE containing a xylene bridge in place of disulfide bond have been synthesized and fully characterized as opioid receptors agon...

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Udgivet i:ACS Med Chem Lett
Main Authors: Stefanucci, Azzurra, Novellino, Ettore, Mirzaie, Sako, Macedonio, Giorgia, Pieretti, Stefano, Minosi, Paola, Szűcs, Edina, Erdei, Anna I., Zádor, Ferenc, Benyhe, Sándor, Mollica, Adriano
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2017
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392763/
https://ncbi.nlm.nih.gov/pubmed/28435535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00044
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