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Negative Stain Single-particle EM of the Maltose Transporter in Nanodiscs Reveals Asymmetric Closure of MalK(2) and Catalytic Roles of ATP, MalE, and Maltose

The Escherichia coli MalE-MalFGK(2) complex is one of the best characterized members of the large and ubiquitous family of ATP-binding cassette (ABC) transporters. It is composed of a membrane-spanning heterodimer, MalF-MalG; a homodimeric ATPase, MalK(2); and a periplasmic maltose receptor, MalE. O...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Fabre, Lucien, Bao, Huan, Innes, James, Duong, Franck, Rouiller, Isabelle
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392688/
https://ncbi.nlm.nih.gov/pubmed/28188291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.757898
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